Biomarkers

Tipologia: Temi di ricerca trasversali

Principal Investigator: Dott. Albertini Riccardo

Active Research projects include:

•Development, evaluation and implementation in clinical practice of disease biomarkers

•Mass-Spectrometry Analysis of Metabolites, Drugs of Abuse, Therapeutic Drug Monitoring

•Quantitative Biomarkers, Digital Imaging in Serological Autoimmune Disease – including Telepathology Network

•Standardization and Metrology for laboratory data comparability

Pasi M, Giardini I, Buscaglia E, Schicchi A, Locatelli CA, Giampreti A, Gallo M, Albertini R, Papa P, Valli A. Prevalence of 3,4-Methylenedioxy-α-Pyrrolidinohexanophenone (3,4-MDPHP) in 465 Suspected Intoxication Cases and Cross-Reactivity Evaluation in an Ecstasy Immunoassay. J Appl Lab Med. 2026;11(1):61-72. doi:10.1093/jalm/jfaf165.
Palladini G, De Luca L, Milani P, Basset M, Di Simone V, Carini V, Mussinelli R, Obici L, Perlini S, Nuvolone M, Albertini R. Indagini di laboratorio per l’esclusione dell’amiloidosi AL: indicazioni pratiche per il cardiologo. G Ital Cardiol. 2026;27(8):539-543. doi:10.1714/4741.47564.
De Gregori S, Capone M, Pellegrini C, Cattadori B, Albertini R. Intragraft tacrolimus: The missing link in heart transplant acute rejection monitoring. JHLT Open. 2026;13:100573. doi:10.1016/j.jhlto.2026.100573.
De Gregori S, Capone M, Pellegrini C, Cattadori B, Albertini R. Therapeutic drug monitoring of Tacrolimus-personalized therapy in heart transplantation: New strategies and preliminary results in endomyocardial biopsies. Pharmaceutics. 2022;14(6):1247. doi:10.3390/pharmaceutics14061247.
Valli A, Ferretti VV, Klersy C, Lonati D, Giardini I, Papa P. Effectiveness of a reliable toxicological analysis for a correct diagnosis of acute intoxication in pediatrics: 2-year experience of an analytical toxicological laboratory. Pediatr Emerg Care. 2022;38(10):e1601-e1605. doi:10.1097/PEC.0000000000002641.

•High throughput chemistry and immunochemistry analyzers HPLC with various detectors, LC-MS/MS

•Optical and immunofluorescence microscopes equipped with digital imaging device and software

•Instruments for serum proteins analysis

•Specialistic Coagulation Testing

•Radioimmuneassay facility

The activities are carried out in the Unit of Clinical Chemistry.

Biochemistry Unit, University of Pavia, Professor Antonio Rossi
Departement of Biology and Biotechnology, University of Pavia, Professoressa Maria Grazia Bottone
Centro di Riferimento Regionale per il Coordinamento della Attività di Laboratorio, Milano
For Toxicology Laboratory: Istituto Superiore di Sanità e Centro Nazionale Antiveleni.