Clinical nutrition and Dietetics

Tipologia: Temi di ricerca trasversali

Principal Investigator: Prof. Caccialanza Riccardo

The Clinical Nutrition and Dietetics Unit coordinates several clinical trials focused on nutritional support in patients with cancer. Current research activities include the use of immunonutrition in head and neck and lung cancer, immunonutrition in patients undergoing radical cystectomy for bladder cancer, nutritional support in gynecological cancers,
and the evaluation of nutritional risk and body composition as prognostic factors. The Unit is also involved in research activities aimed at developing innovative artificial intelligence–based technologies to optimize the identification and management of nutritional risk in hospitalized patient.

Cereda E, Casirati A, Gonzalez MC, Souza NC, Prado CM, Ford KL, Mauricio SF, Correia MITD, Pedrazzoli P, Caccialanza R. Muscle Health and Prognosis in Patients With Cancer: New Insights. J Cachexia Sarcopenia Muscle. 2026 Jun;17(3):e70292. doi: 10.1002/jcsm.70292.
Cereda E, Borioli V, Caraccia M, Uggè A, De Simeis F, Bruno R, Corsico AG, Di Sabatino A, Pedrazzoli P, Caccialanza R. Systematic high-calorie, high-protein oral nutritional support in hospitalized, moderately hypophagic patients at nutritional risk: A randomized-controlled trial. Clin Nutr. 2026 Jan;56:106532. doi: 10.1016/j.clnu.2025.11.017.
Mattavelli E, Da Prat V, Corallo S, Tartara A, Figini S, De Simeis F, Marino S, Uggè A, Caccialanza R, Pedrazzoli P, Lasagna A. Harnessing the gut microbiota in extra-intestinal cancers: from causal evidence to immunotherapy strategies. Immunotherapy. 2026 Feb;18(3):223-235.
Cereda E, Casirati A, Klersy C, Nardi M, Vandoni G, Agnello E, Crotti S, Masi S, Ferrari A, Pedrazzoli P, Caccialanza R; ONCO-BIVA Collaborative Group. Bioimpedance-derived body composition parameters predict mortality and dose-limiting toxicity: the multicenter ONCO-BIVA study. ESMO Open. 2024 Aug;9(8):103666. doi: 10.1016/j.esmoop.2024.103666. Epub 2024 Aug 12. PMID: 39137479; PMCID: PMC11369426.
Silvestris N, Aprile G, Tessitore D, Mentrasti G, Cristina Petrella M, Speranza D, Casirati A, Caccialanza R, Cinieri S, Pedrazzoli P; Italian Intersociety Working Group for Nutritional Support in Cancer Patients. Harnessing tumor metabolism during cancer treatment: a narrative review of emerging dietary approaches. Crit Rev Oncol Hematol. 2024 Nov 22:104571. doi:10.1016/j.critrevonc.2024104571.

Bioelectrical impedance phase sensitive single-frequency analyzers (Nutrilab, Akern®);
hand grip strength dynamometer (DynX®™);
medical scales (Wunder®);
medical image analysis software sliceOmatic (v5.0, TomoVision).

Together with the Oncology Unit, our Team is coordinating the Intersociety (AIOM-SINPE-FAVO-SICO-ASAND-AIRO-FNOPI) Italian Working Group for Nutritional Support in Cancer Patients and the Survivorship Care & Nutritional Support Working Group of Alliance Against Cancer (ACC). It is also collaborating with the Gruppo Italiano per il Trapianto di Midollo Osseo (GITMO) and the Cellular Therapy and Immunobiology Working Party (CTIWP) and the Nurses Group (NG) of the European Society for Blood and Marrow Transplantation (EBMT). Our Clinical Nutrition and Dietetics Unit is an Hub center of Regione Lombardia with regards to Nutrition in Oncology, Short Bowel Syndrome and Artificial Nutrition.

GROUP MEMBERS:

Caludia Sivieri, Eugenio Valentini, Anna Amplatz, Ilenia Barca, Valeria Borioli, Anna Maria Crippa, Maria Zugnoni, Marilisa Caraccia, Annalisa Opizzi, Gabriella Peroni, Silvia Crotti, Sara Masi, Francesca De Simeis, Anna Uggè, Elisa Mattavelli, Elisabetta Montagna.

Prof. Caccialanza Riccardo